食管颗粒细胞瘤1例并国内文献复习

Granular cell tumor of the esophagus: Report of one case and review of the Chinese literature

背景颗粒细胞瘤(granular cell tumor,GCT)是少见的软组织肿瘤,具有潜在的恶性.虽然临床表现缺乏特异性,在内镜和超声内镜下有其独特的表现.病例简介患者因上腹部疼痛20 d就诊,腹部查体无阳性体征.胃镜显示距门齿39 cm食管右侧壁有一0.5 cm×0.7 cm黏膜下隆起,表面呈淡黄色,光滑,活检钳触之质硬,活动.超声内镜:病灶处呈稍高回声改变,起源于黏膜下层.行黏膜下肿瘤剥离治疗后标本送检证实为食管颗粒细胞瘤.结论食管颗粒细胞瘤临床少见,但该病在内镜及病理学上有特异性表现.因食管颗粒细胞瘤有潜在恶性,应积极进行内镜下切除治疗,对于恶性病变或侵及肌层、病变范围大者仍需外科治疗.

BACKGROUND Granular cell tumor(GCT)is a rare soft tissue tumor that has malignancy potential.Despite the lack of specific clinical manifestations,GCT has special gastroscopic and endoscopic ultrasonographic manifestations.CASE SUMMARY A male patient was admitted because of epigastric pain for 20 d,and there were no positive signs of abdominal examination.Gastroscopy showed that there was a 0.5 cm×0.7 cm submucous eminence on the right wall of the esophagus at 39 cm from the incisor,and the tumor had a yellowish and smooth surface,and was hard and movable on touch.Endoscopic ultrasonography showed that the lesion was slightly hyperechoic and originated from the submucosa.After endoscopic submucosal dissection,it was confirmed pathologically to be an esophageal GCT.CONCLUSION Esophageal GCT is clinically rare and has specific endoscopic and pathological manifestations.Because of the malignancy potential,active endoscopic treatment is necessary.Surgical treatment is still needed for malignant lesions or lesions invading the muscle layer.