糖尿病骨髓微血管病变影像学研究进展

Research progress in imageology of diabetic bone marrow microangiopathy

糖尿病骨病是糖尿病并发症,糖尿病患者患骨折、骨质疏松的风险明显增加,且难以治愈,严重危害人们健康.越来越多的研究表明糖尿病骨髓病变与微血管病变密不可分,影像学可以从多方面无创性评价骨髓,如X线可测量骨密度,CT可评估骨微结构的变化,MRI可以评估其血流灌注及骨髓脂肪沉积等,为糖尿病骨病的病理生理机制提供可视化影像学的研究证据.笔者就糖尿病骨病与骨髓微血管病变、骨密度、骨结构、骨代谢及骨折风险评估的影像学研究进展进行综述.

Diabetic bone disease is a complication of diabetes. Diabetic patients have significantly increased risk of fracture and osteoporosis, which is difficult to cure and seriously endangers people's health. More and more studies have shown that diabetic bone disease are inseparable from microangiopathy. Imaging can evaluate bone marrow noninvasively from various aspects, such as X-ray can measure bone mineral density, CT can assess changes in bone microstructure, MRI can evaluate the perfusion of blood flow and the deposition of bone marrow fat deposition, which can provide visual imaging research evidence for the pathophysiological mechanism of diabetic bone disease. This article reviews the advances in imaging studies on the relationship between diabetic bone disease and diabetic microvascular disease on bone, bone mineral density, bone structure, bone metabolism, and risk assessment of fracture.