非手术方法治愈新生儿先天性皮肤缺损11例

Non-surgical treatment of congenital skin defects in 11 neonates

目的探讨新生儿先天性皮肤缺损的非手术方法临床救治及创面护理方法.方法11例先天性皮肤缺损患儿入院后均进行全面评估各项生命指标及创面情况,患儿均于恒温保温箱内护理,个体化抗休克、抗感染及补液治疗,维持各器官功能,所有皮肤缺损创面用0.01%苯扎氯胺溶液清洗消毒,外用0.01%苯扎氯胺溶液湿敷包扎治疗,促进上皮原位再生.观察新生上皮生长情况,在不损伤患儿组织情况下,适时取创面组织做病理检查,观察上皮再生情况.结果本组11例新生儿均恢复良好,无死亡或严重并发症发生.1例患儿自动出院后失访.随访10例,8例创面愈合良好,无明显瘢痕形成.结论先天性皮肤缺损患儿及早的采用非手术法进行治疗,可以较好地促进创面的痊愈,保障结构与功能恢复.

Objective To explore nonsurgical clinical cure wound nursing methods for newborn congenital skin defect. Methods 11 cases of children with congenital skin defect after admission were to conduct a comprehensive assessment of various life index and wound, children are in constant temperature heat preservation box nursing, individual lines of shock resistance, resistance to shock and rehydration treatment, maintain the function of each organ, all skin defect wound cleaning and disinfection with 0.01% Benzalkonium Chloride Solution, 0.01% Benzalkonium Chloride Solution hydropathic compress on skin defect wound,promote epithelial regeneration in situ.To observe the epithelial growth, new without damage children organization, timely take tissue pathological examination, to observe the epithelial regeneration.Results This group of 11 cases of newborn were recovered well, without death or severe complications occurred in court.1 cases automatically lost to follow-up after discharge.Good follow-up of 10 cases, 8 cases of wound healing, no obvious scar formation and function of activity is not affected, parts of light pigmentation.Local mild scar hyperplasia, 1 case had no significant effect of the activities and functions.1 case appeared obvious scar hyperplasia, mild limited right knee function activities, quadratic function activity markedly improved after surgery.Conclusion Children with congenital skin defect of early adoption of non-surgical method of treatment, can better promote wound healing and reduce scar formation.