化疗联合腹腔镜远端胃癌根治术治疗胃癌的疗效

Effect of Chemotherapy Combined With Laparoscopic Radical Treatment of Distal Gastric Cancer

目的研究新辅助化疗联合腹腔镜远端胃癌根治术治疗进展期胃癌疗效与安全性分析。方法选择2017年6月—2018年8月进展期胃癌患者作为本次研究对象,并采用电脑随机法将200例进展期胃癌患者进行分组,主要包括两组,观察组实施新辅助化疗联合腹腔镜远端胃癌根治术治疗;对照组实施腹腔镜远端胃癌根治术治疗。结果观察组进展期胃癌患者治疗总有效率高于对照组(P<0.05)。观察组的手术时间、术中出血量、术后下床活动时间、术后肛门排气时间、住院时间与对照组相比较,差异具有统计学意义(P<0.05)。观察组进展期胃癌患者并发症发生率与对照组比较,差异无统计学意义(P>0.05)。结论新辅助化疗联合腹腔镜远端胃癌根治术治疗进展期胃癌的疗效十分显著。

Objective To study the efficacy and safety of neoadjuvant chemotherapy combined with laparoscopic distal gastrectomy for advanced gastric cancer.Methods From June 2017 to August 2018,200 patients with advanced gastric cancer were randomly divided into two groups,the observation group received neoadjuvant chemotherapy combined with laparoscopic radical gastrectomy,and the control group received laparoscopic radical gastrectomy.Results The total effective rate of advanced gastric cancer patients in the observation group was higher than that in the control group(P<0.05).There were significant differences in operation time,intraoperative bleeding volume,time of getting out of bed after operation,time of anal exhaust after operation and hospital stay between the observation group and the control group(P<0.05).There was no significant difference in the incidence of complications between the observation group and the control group(P>0.05).Conclusion Neoadjuvant chemotherapy combined with laparoscopic radical gastrectomy for advanced gastric cancer is very effective.