急性脑梗死患者凝血功能和D-二聚体变化

Changes of Coagulation Function and D-Dimer in Patients With Acute Cerebral Infarction

目的探究急性脑梗死患者的凝血功能指标与D-二聚体变化。方法选择本院2017年9月—2018年5月收治的急性脑梗死患者62例作为研究组,同时期体检科正常患者62例作为对照组,抽取两组患者血液进行实验室检查,比较两组患者的血浆凝血酶原时间(Prothrombintime,PT)、纤维蛋白原(fibrinogen,FIB)、活化部分凝血活酶时间(activated partial thromboplastin time,APTT)、血浆凝血酶时间(thrombintime,TT)和D-二聚体水平(D-Dimer,DD)。结果两组的血浆凝血酶原时间、活化部分凝血活酶时间和血浆凝血酶时间差异无统计学意义(P>0.05),纤维蛋白原与D-二聚体水平高于对照组(P<0.05)。结论纤维蛋白原与D-二聚体检测可辅助诊断急性脑梗死。

Objective To explore the changes of coagulation indexes and D-dimer in patients with acute cerebral infarction.Methods 62 patients with acute cerebral infarction admitted to our hospital from September 2017 to May 2018 were selected as the study group,while 62 patients with normal physical examination department were selected as the control group.Blood of the two groups were extracted for laboratory examination.Plasma prothrombin time(PT),fibrinogen(FIB),activated partial thromboplastin time(APTT),plasma thrombin time(TT),and D-Dimer(DD).Results There was no significant difference in plasma prothrombin time,activated partial thromboplastin time and plasma thrombin time between the two groups(P>0.05).fibrinogen and D-Dimer levels were higher than those of the control group(P<0.05).Conclusion Detection of fibrinogen and D-Dimer can assist diagnosis of acute cerebral infarction.