维生素E辅助钙剂治疗妊娠高血压的疗效及妊娠结局分析

Effect of vitamin E calcium supplement on pregnancy induced hypertension and analysis of pregnancy outcome

目的:探讨维生素E辅助钙剂治疗妊娠高血压的疗效及对妊娠结局的影响.方法:回顾性分析2015年1月~2017年7月期间在我院接受治疗的140例妊娠高血压患者的诊疗情况.按照治疗方式的不同,将患者分为观察组和对照组,每组70例.对照组给予硫酸镁、硝苯地平等常规治疗,观察组在此基础上给予维生素E辅助钙剂治疗.比较两组的临床治疗效果、治疗前后的平均动脉压和尿蛋白以及孕产妇和围生儿结局.结果:观察组治疗的总有效率为94.3%,显著高于对照组(84.3%),两组比较差异有统计学意义.治疗后,两组的平均动脉压和尿蛋白均明显降低,且观察组明显低于对照组,两组比较差异有统计学意义.观察组产妇的自然分娩率明显高于对照组,早产、产后出血、胎儿宫内窘迫及新生儿窒息的发生率均明显低于对照组,两组比较差异有统计学意义.结论:维生素E辅助钙剂治疗妊娠高血压的疗效良好,可显著改善妊娠结局,值得在临床上推广.

Objective To investigate the effect of vitamin E calcium supplement on pregnancy induced hypertension and its effect on pregnancy outcome. Methods A retrospective analysis was conducted on the diagnosis and treatment of 140 cases of pregnancy induced hypertension from January 2015 to July 2017 in our hospital. According to the different ways of treatment, the patients were divided into observation group and control group, 70 cases in each group. The control group was given conventional treatment, such as Magnesium Sulfate and nifedipine, while the observation group was given vitamin E and calcium supplement. The clinical effects, the mean arterial pressure and urine protein, and the outcome of maternal and perinatal outcomes were compared between the two groups. Results The total effective rate of the observation group was 94.3%, which was significantly higher than that of the control group (84.3%). After treatment, the mean arterial pressure and urine protein in the two groups were significantly lower than those before the treatment, and the above indexes in the observation group were all lower than those in the control group. The natural childbirth rate of the observation group was significantly higher than that of the control group, the incidence of premature delivery and postpartum hemorrhage was lower than that of the control group. The incidence of fetal distress and neonatal asphyxia in the observation group were significantly lower than those in the control group. Conclusion Vitamin E calcium supplement is effective in the treatment of pregnancy induced hypertension. It can significantly improve pregnancy outcome and is worthy of clinical promotion.