重症肌无力非运动症状的临床研究进展

The clinical research progress of non-motor symptoms in myasthenia gravis

重症肌无力是一种神经-肌肉接头传递功能障碍的获得性自身免疫性疾病,其主要临床表现为部分或全身骨骼肌无力和极易疲劳,活动后症状加重,经休息和胆碱酯酶抑制剂治疗后症状减轻。近年来研究发现,重症肌无力除肌肉无力、吞咽困难等运动症状外,还伴有非运动症状。现就重症肌无力非运动症状的临床研究进展进行综述。

Myasthenia gravis (MG) is an acquired autoimmune disease involving neuromuscular junctions transmit dysfunction. The main clinical manifestations are partial or systemic skeletal muscle weakness and extreme fatigue, increased symptoms after activity, relieved after rest and treatment with cholinesterase inhibitors. However, recent studies have found that patients of MG are not only accompanied by motor symptoms such as muscle weakness and dysphagia, but also with non-motor symptoms. This article reviews the clinical research progress of non-motor symptoms in MG.