摘要
目的 评估Ⅲ型便携式睡眠呼吸监测仪(PM)对中国成人阻塞性睡眠呼吸暂停(OSA)患者的诊断价值.方法 收集2015年10月至2019年3月就诊于北京大学人民医院睡眠中心的89例疑诊OSA的成年人,先用Nox-T3进行1次整夜无人值守的家庭睡眠呼吸暂停监测(HSAT),然后进行整夜实验室多导睡眠监测(PSG),同时进PM的监测.PM记录先使用自动分析进行评分,然后进行人工判读,评价PSG的呼吸暂停低通气指数(AHI)和PM的呼吸紊乱指数(RDI)相关性.结果 HSAT的RDI为(30.0±20.9)次/h,实验室PM的RDI为(33.4±22.4)次/h,PSG的AHI为(35.1±23.7)次/h,三组间有显著差异(P<0.001).但HSAT的RDI与PSG的AHI(r=0.877,P<0.001)、实验室PM的RDI与PSG的AHI结果(r=0.962,P<0.001)显著相关.PSG的AHI与HSAT的RDI之间差值均值为4.4次/h,一致性界限为-17.6~26.5;PSG的AHI与实验室PM的RDI之间差值均值为1.4次/h,一致性界限为-11.3~14.2.当AHI≥5次/h时,与PSG相比,HSAT具有98.8%的敏感度,40.0%的特异度.当AHI≥15次/h时,HSAT具有91.5%的敏感度,76.5%的特异度.结论 Ⅲ型PM对中国成人OSA患者具有较好的诊断价值,与PSG具有良好的一致性.
Objective To evaluate the utility of a portable monitor at home for diagnosis of obstructive sleep apnea (OSA) in Chinese adults. Methods Eighty nine patients suspected of OSA underwent overnight, unattended home sleep apnea testing (HSAT) with a portable monitor(Nox-T3, Nox Medical Inc. Iceland)followed by an in-laboratory polysomnogram (PSG) with simultaneous portable monitor (PM) recording within one week. PSG and PM recorder were scored according to recommended guidelines by independent technicians. The correlation between PSG apnea hypopnea index (AHI) and PM respiratory disturbance index (RDI) were evaluated. Results Sleep testing showed RDI was (30.0 ± 20.9) events/h on HSAT, and (33.4±22.4) events/h on in-laboratory PM recording. Apnea-hypopnea index (AHI) on PSG was (35.1 ± 23.7) events/h. There was significantly statistical difference among the three group (P<0.001). Both RDI on HSAT and RDI on in-laboratory PM correlated significantly with AHI on PSG (r=0.877, P<0.001 and r=0.962, P<0.001, respectively). Bland-Altman analysis of AHI on PSG versus RDI on HSAT showed a mean difference of 4.4 events/h;limits of agreement was -17.6 to 26.5 events/h. Closer agreements were present when comparing the simultaneous recordings, with AHI on PSG versus RDI on in-laboratory PM showing a mean difference of 1.4 events/h, and limits of agreement was-11.3 to 14.2 events/h. Based on a threshold of AHI≥5 events/h, RDI on HSAT had 98.8% sensitivity, 40.0% specificity. Using an AHI ≥ 15 events/h, RDI on HSAT had 91.5%sensitivity, 76.5%specificity. Conclusion Type 3 PM has a good diagnostic value for adult OSA patients and there is close agreement between the Type 3 portable monitor and PSG.
作者
温永飞
常远
许力月
董霄松
赵龙
张雪丽
李静
左玉花
张伟
高莹卉
韩芳
Wen Yongfei;Chang Yuan;Xu Liyue;Dong Xiaosong;Zhao Long;Zhang Xueli;Li Jing;Zuo Yuhua;Zhang Wei;Gao Yinghui;Han Fang(Department of Pulmonary and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China;Department of Pulmonary and Critical Care Medicine, Peking University International Hospital, Beijing 102206, China;PKU-UPenn Sleep Center, Peking University International Hospital, Beijing 102206, China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2019年第38期2994-2999,共6页
National Medical Journal of China