间充质干细胞与外泌体和富血小板血浆在创面修复中的作用研究进展

Advances in the research of effects of mesenchymal stem cells, exosomes, and platelet-rich plasma in wound repair

在我国,很多患者由于创面修复困难,创面逐渐转变成为一种慢性疾病,给家庭和社会带来沉重负担。目前关于创面修复的研究较多,然而其机制仍不明确。越来越多的研究表明,间充质干细胞、外泌体和富血小板血浆可通过对创面修复的各个阶段起不同的重要作用,有效促进创面修复。本文就间充质干细胞、外泌体和富血小板血浆在创面修复中的作用及机制进行综述。

Due to difficult healing, wounds become chronic diseases in many patients, and bring heavy burden to family and society in China. Although there are many studies about wound repair at present, its mechanism remains unclear. An increasing number of studies showed that mesenchymal stem cells (MSCs), exosomes, and platelet-rich plasma (PRP) play different important roles in the regulation of different phases of wound repair. This review focuses on the function and mechanism of MSCs, exosomes, and PRP in wound repair.