摘要
The interaction between extracellular matrices and cancer cells plays an important role in regulating cancer cell behaviors. In this article, we use matrigel to mimic extracellular matrices and investigate experimentally how matrigel influences the shape and dynamics of breast cancer cells(MDA-MB-231-GFP cells). We find that matrigel facilitates cancer cells' migration and shape deformation. The influences of the matrigel concentration are also reported.
The interaction between extracellular matrices and cancer cells plays an important role in regulating cancer cell behaviors. In this article, we use matrigel to mimic extracellular matrices and investigate experimentally how matrigel influences the shape and dynamics of breast cancer cells(MDA-MB-231-GFP cells). We find that matrigel facilitates cancer cells’ migration and shape deformation. The influences of the matrigel concentration are also reported.
作者
Teng Ye
Feng Qiu
叶腾;邱峰(First Clinical Medical College,Nanchang University,Nanchang 330006,China;Department of Oncology,First Affiliated Hospital of Nanchang University,Nanchang 330006,China)
基金
support of the CAS Key Lab of Soft Matter Physics
