胺碘酮治疗充血性心力衰竭合并室性心律失常56例临床分析

Clinical Analysis of Amiodarone in the Treatment of 56 Patients with Congestive Heart Failure Complicated with Ventricular Arrhythmia

目的探讨胺碘酮治疗充血性心力衰竭合并室性心律失常的临床效果。方法方便选取该院于2016年3月—2018年3月所收治的充血性心力衰竭合并室性心律失常患者112例为研究对象,将其随机分为实验组和对照组,对照组行常规治疗,实验组于对照组基础上加施胺碘酮治疗,观察并比较两组患者治疗前后临床指标变化情况、临床疗效及不良反应的发生情况。结果两组患者治疗前各项临床指标情况比较差异无统计学意义(t=0.275、0.328、1.459,P>0.05),治疗后均有所改善,实验组治疗后各项临床指标情况较对照组明显更优,组间比较差异有统计学意义(t=4.263、13.746、6.988,P<0.05);实验组临床治疗总有效率为94.64%,较对照组的76.79%明显更高,组间比较差异有统计学意义(χ^2=7.292,P<0.05)。结论胺碘酮治疗充血性心力衰竭合并室性心律失常可有效提高临床疗效,改善患者身体状况,且不良反应的发生率低,具较高安全性,值得在临床当中推广使用。

Objective To investigate the clinical effect of amiodarone in the treatment of congestive heart failure with ventricular arrhythmia.Methods Convenient selected a total of 112 patients with congestive heart failure and ventricular arrhythmia admitted to our hospital from March 2016 to March 2018 were enrolled in the study.They were randomly divided into experimental group and control group,and the control group received routine treatment.The experimental group was treated with amiodarone on the basis of the control group.The changes of clinical indicators,clinical efficacy and adverse reactions were observed and compared before and after treatment.Results There were no significant differences in the clinical parameters between the two groups before treatment(t=0.275,0.328,1.459,P>0.05),all improved after treatment,after treatment in the experimental group,the clinical indicators were significantly better than the control group,and there were significant differences between the groups(t=4.263,13.746,6.988,P<0.05);the total effective rate of clinical treatment in the experimental group was 94.64%was significantly higher than 76.79%of the control group,and there was a significant difference between the groups(χ^2=7.292,P<0.05).Conclusion Amiodarone in the treatment of congestive heart failure combined with ventricular arrhythmia can effectively improve the clinical efficacy,improve the patient's physical condition,and the incidence of adverse reactions is low,with high safety,it is worth promoting in clinical practice.