多囊卵巢综合征患者易合并自身免疫性甲状腺疾病的相关机制研究进展

Research Progress in Mechanism of Polycystic Ovary Syndrome Patients with Autoimmune Thyroid Diseases

多囊卵巢综合征(PCOS)为最常见的女性内分泌疾病,常伴有血糖、血脂等内分泌代谢紊乱及生殖功能障碍,其长久发展可增加患心血管疾病、糖尿病、脂肪肝等的风险,严重影响患者的生活质量。PCOS妇女易合并自身免疫性甲状腺疾病,而自身免疫性甲状腺疾病引起的甲状腺功能异常可加重PCOS妇女的血糖、血脂的代谢紊乱和生殖功能障碍。了解PCOS易合并自身免疫性甲状腺疾病的相关机制对患者的诊疗及疾病预防具有重要意义。

Polycystic ovary syndrome(PCOS) as the most common female endocrine disease,is commonly accompanied by metabolic abnormalities such as pathoglycemia and dyslipidemia and reproductive dysfunction.Its long-term development can increase the risk of suffering cardiovascular disease,diabetes,fatty liver,and seriously affect the patients’ quality of life.Women with PCOS are prone to suffer autoimmune thyroid disease.Thyroid dysfunction caused by autoimmune thyroid disease can aggravate pathoglycemia,dyslipidemia and reproductive dysfunction in women with PCOS.Understanding the pathogenesis of PCOS with autoimmune thyroid diseases is of great significance for the diagnosis,treatment and disease prevention.