氧化应激与慢性阻塞性肺疾病的相关性研究

Correlation between oxidative stress and chronic obstructive pulmonary disease

慢性阻塞性肺疾病是以一种以气流受限为特殊的慢性呼吸系统疾病,以反复的咳嗽、咳痰、喘息气短为主要表现,严重影响患者的生活质量,加重患者的经济负担,治疗上除了按时按需吸入支气管舒张剂及低流量吸氧外,对于气道和肺脏的慢性炎性反应和抗氧化应激的控制也十分重要,本文就慢性阻塞性肺疾病在抗氧化失衡方面的治疗进行综述以指导临床用药。

Chronic obstructive pulmonary disease is a chronic respiratory disease with special airflow limitation,it is mainly characterized by repeated cough,cough,and shortness of breath,which seriously affects the quality of life of patients,aggravates the economic burden of patients.In the aspect of treatment,in addition to timely inhalation of bronchodilators and low-flow oxygen inhalation,it is also important for the control of chronic inflammatory response and anti-oxidative stress in airways and lungs.This article reviews the treatment of chronic obstructive pulmonary disease in terms of antioxidant imbalance,in order to guide clinical medication.