摘要
A novel dual-modal fluorometric and colorimetric method was developed for glucose detection using MnO2 sheets and carbon quantum dots(CQDs). The glucose could be oxidized by glucose oxidase, in accompanied witli the fbnnation of H2O2 intennediate, which resulted in the decomposition of MnO2 sheets, as well as tlie MnO2 sheets(brown) changed to Mn^2+ ions(colorless), which induced the absorption of MnO2 sheet decreased and the fluorescence of CQDs increased, consequently. The linear detection ranges of glucose are 5-1000 μmol/L by fluorescent method and 5-60 μmol/L by colorimetric method. The limits of detection of these two measurements are 2.11 and 2.18 μmol/L, respectively. This method is easy to conduct, has reasonable sensitive and selectivity, and could be applied for the glucose detection in real human senim.
基金
Supported by the National Natxiral Science Foundation of China(No.21305032)
the Postdoctoral Science Foundation of China(Nos.2014M551522,2018M632238)
the Natural Science Foundation of Jiangsu Province,China(No.BK20160490)
the Priority Academic Program Development(PAPD) of Jiangsu Higher Education Institutions,China
tlie Open Research Fund of Henan Key Laboratory of Biomolecular Recognition and Sensing,China(No.HKLBRSK1803).
