植物OSCA1家族的起源与进化

Origin and Evolution of OSCA1 Family in Plants

OSCA(reduced hyperosmolality-induced[Ca2+]iincreasechannel)是高渗性门控非选择性的钙渗透阳离子通道,它在感受外源和内源的渗透变化以及调节植物生长发育中起着关键作用。目前关于OSCA1家族的研究大多集中在功能方面,而关于系统发育分析的研究较少,尤其是在植物界没有采集大量的样本并进行深入研究。通过对植物界目前已完成全基因组测序的82个物种OSCA1家族的系统发育分析来探究该家族的起源与进化。研究表明,OSCA1在被子植物中可以分为四大分支(OSCA1.2、OSCA1.5、OSCA1.7和OSCA1.8),且该家族在整个高等植物中为一个单系;在OSCA1家族的8个成员中均发生了基因重复事件;OSCA1家族在低等到高等植物中的数量分布大致呈现递增趋势。以上结果不仅可以完善植物界中OSCA1家族的进化历史,而且能够为进一步研究其功能提供充足的理论依据。

OSCA (reduced hyperosmolality-induced [Ca 2+] i increase channel) are hyperosmolarity-gated non-selective cation channels that permeates calcium ions. OSCA family plays a key role in sensing exogenous and endogenous osmotic changes and regulating plant growth and development. Most of the current researches on the OSCA1 family focused on functions, but few on phylogenetic analysis.There were no further studies using a large number of samples in plants.In this study, we investigated the origin and evolution of OSCA1 family in 82 species in plants that had completed genome sequencing. The results were as follows:OSCA1s in angiosperms could be divided into four branches (OSCA1.2, OSCA1.5, OSCA1.7 and OSCA1.8), and that OSCA1s was monophyletic in the whole higher plants. There were gene duplication events occurred in all 8 members of OSCA1 family.The number of OSCA1 family in lower to higher plants showed an increasing trend in general.The above results could be not only helpful for us to know the phylogeny of OSCA1 family in plants, but also helpful for further study of its functions.