穿刺血肿引流术治疗高血压脑出血的有效性及安全性研究

Study on effectiveness and safety of puncture hematoma drainage in treatment of hypertensive cerebral hemorrhage

目的探讨穿刺血肿引流术治疗高血压脑出血的有效性及安全性。方法选取我院2017年11月~2018年11月共94例高血压脑出血患者作为研究对象,根据手术方法的不同,分为研究组和常规组各47例。常规组通过小骨窗血肿清除术进行治疗,研究组通过微创穿刺血肿引流术进行治疗,对比两组临床疗效。结果两组优良率比较,差异无统计学意义(P>0.05)。治疗前,两组TNF-α、IL-6以及hs-CRP水平差异无统计学意义(P>0.05);治疗后,两组TNF-α、IL-6以及hs-CRP水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。研究组并发症发生率低于常规组,差异有统计学意义(P<0.05)。结论微创穿刺血肿引流术治疗高血压脑出血临床疗效明显,能有效缓解机体炎症水平,促进患者术后康复,改善患者预后,且安全性较高,并发症发生率相对较低,值得推广应用。

Objective To explore effectiveness and safety of puncture hematoma drainage in treatment of hypertensive cerebral hemorrhage. Methods 94 patients with hypertensive cerebral hemorrhage in our hospital from November 2017 to November 2018 were selected as the research objects.According to the different surgical methods,they were divided into the study group and the conventional group,with 47 cases in each group.The conventional group was treated with small bone window hematoma removal surgery while the study group was treated with minimally invasive puncture hematoma drainage.Clinical curative effects of the two groups were compared. Results There was no statistically significant difference between the two groups in the excellent and good rate of treatment (P > 0.05).Before treatment,there were no statistically significant differences in TNF-α, IL-6 and hs- CRP levels between the two groups (P > 0.05).After treatment,TNF-α,IL-6 and hs-CRP levels in the two groups were lower than those before treatment,and the levels in the study group were lower than those in the control group.The difference was statistically significant (P < 0.05).The incidence of complications in the study group was lower than that in the conventional group, and the difference was statistically significant (P < 0.05). Conclusion Minimally invasive puncture hematoma drainage in treatment of hypertensive intracerebral hemorrhage has significant clinical curative effects.It can effectively relieve the level of inflammation in the body,promote postoperative rehabilitation of patients and improve the prognosis of patients.It has high safety and relatively low incidence of complications,which is worthy of promotion and application.