跨高原心血管疾病研究进展

Research Progress on Cardiovascular Disease in Trans-Plateau Regions

目的:了解跨亚高原到高原区域心血管疾病的发病特点。方法:复习文献,对近年来有关这一区域的心血管疾病论著进行综述。结果:跨高原地区指跨越亚高原到高原的区域(海拔1000~3500m),其疾病尤其是心血管疾病的发生、发展机制有不同的特点,目前少见专门针对跨高原地区心血管疾病的研究。结论:海拔1000~3500m跨高原心血管疾病的研究较少,缺乏系统性研究,病理生理机制尚不清楚。提出跨高原心血管疾病的概念并进行深入研究,对短期暴露或久居于跨高原地区人群的心血管疾病防治有重要意义。

Objective: To understand the characteristics of cardiovascular disease in the region from the trans-sub-plateau to the plateau. Methods: Study the literature and review the recent papers on cardiovascular disease in this region. Results: Trans-plateau regions refers to the areas cross sub-plateau to plateau area(altitude about 1 000-3 500 m). Cardio-vascular diseases have different characteristics and mechanism in these regions. There are few studies that specifically address cardiovascular disease across the transplateau regions. Conclusion: There are few studies on cardiovascular diseases across the plateau at an altitude of 1 000-3 500 m, without systematic studies, and the pathophysiological mechanism is still unclear. This paper proposes the concept of trans-plateau cardiovascular disease and conducts in-depth research, which is of great significance for the prevention and treatment of cardiovascular disease in people with short-term exposure or long-term living in trans-plateau area.