肠道菌群与慢性肝病相关研究进展

Research progress on intestinal flora and chronic liver diseases

肠道菌群对人体健康的影响日益引起国内外关注.肠道菌群与肝病发生发展的相关研究也越来越多.肠道菌群不但直接影响肠道疾病,其也能通过"肠肝对话"影响肝脏代谢和免疫,在多种慢性肝病如非酒精性脂肪性肝病、酒精性肝病、肝硬化和原发性肝癌的发生发展中具有重要作用.本文就肠道菌群与多种肝病的相互作用及在肝病治疗中的应用进行综述.

The influence of intestinal flora on human health has attracted increasing attentions at home and abroad. Studies on intestinal microflora and the occurrence and development of liver diseases are emerging one after another. Intestinal flora not only directly affects the intestinal diseases of the organs in which it is located, but also affects many functions such as liver metabolism and immunity through “entero-hepatic dialogue”, it plays an important role in the occurrence and development of a variety of chronic liver diseases, such as non-alcoholic fatty liver disease, alcoholic liver disease, liver cirrhosis and primary liver cancer. This article reviewed the interaction between intestinal flora and various liver diseases and its application in the treatment of liver diseases.