前置胎盘剖宫产产后出血行欣母沛与宫腔填纱联合治疗的效果分析

Analysis of the effect of hemabate combined with uterine cavity filling gauze on postpartum hemorrhage in patients with placenta previa cesarean section

目的探讨前置胎盘剖宫产产后出血行欣母沛与宫腔填纱联合治疗的效果,以便为前置胎盘剖宫产产后出血的临床治疗提供理论与实践依据.方法选取2016年1月~2018年1月本院妇产科收治的前置胎盘剖宫产产后出血患者合计93例进行回顾性分析,在经本院医学伦理委员会批准的基础上按随机数字表法(RNTM)将其分成三组,联合组采用欣母沛与宫腔填纱联合治疗,对照组单纯采用欣母沛治疗,实验组单纯采用宫腔填纱治疗,比较三组患者术中、术后出血量,血压、体温等指标的变化情况.结果联合组术中出血量与对照组和实验组相比均有统计学差异(P<0.05),对照组与实验组相比无明显差异(P>0.05);联合组术后2h、24 h出血量与实验组、对照组相比有统计学差异(P<0.05),实验组与对照组相比有差异(P<0.05).三组患者治疗后血压、体温比较,联合组优于实验组及对照组,有统计学差异(P<0.05),三组治疗前无明显差异(P>0.05).对照组与实验组并发症发生率比较无显著差异(P>0.05),联合组的并发症发生率均低于实验组、对照组,差异显著(P<0.05).结论在前置胎盘剖宫产产后出血患者的临床治疗中,欣母沛与宫腔填纱联合与单纯的予以欣母沛或宫腔填纱相比临床疗效更佳,有良好的临床应用价值.

Objective To investigate the effect of hemabate combined with uterine cavity filling gauze on postpartum hemorrhage in patients with placenta previa cesarean section, in order to provide theoretical and practical basis for clinical treatment of postpartum hemorrhage in placenta previa cesarean section. Methods A total of 93 postpartum hemorrhage patients with placenta previa cesarean section admitted to our department from January 2016 to January 2018 were retrospectively analyzed. And the patients were divided into three groups according to random numbers on the basis of the approval of medical ethics committee in our hospital. The combined group was treated with hemabate and uterine cavity filling gauze. The control group was treated with hemabate alone. The experimental group was treated with uterine cavity filling gauze alone. The changes of intraoperative and postoperative blood loss, blood pressure and body temperature in three groups of patients were compared. Results There was a statistically significant difference in the intraoperative blood loss between the combined group and the control group and the experimental group(P<0.05). There was no significant difference in the intraoperative blood loss between the control group and the experimental group(P>0.05). The amount of bleeding in the combined group was statistically different from that in the experimental group and the control group 2h and 24h after operation(P<0.05). And there was a difference between the experimental group and the control group(P<0.05). The blood pressure and body temperature after treatment in the combined group were better than those in the experimental group and control group(P<0.05), and there was no significant difference before treatment among three groups(P>0.05). There was no significant difference in the incidence rate of complications between the control group and the experimental group(P>0.05). The incidence rate of complications of the combined group was lower than that of the experimental group and the control group, and the difference was significant(P<0.05). Conclusion In the clinical treatment of postpartum hemorrhage patients with placenta previa cesarean section, Xinmupei combined with uterine cavity filling gauze is more effective than simple Xinmupe or uterine cavity filling, and it has good clinical application value.