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动物响应亚磁场的生化和分子机制

The biochemical and molecular mechanisms underlying the effects of the hypomagnetic field in animals
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摘要 磁感应强度远低于地磁场(geomagnetic field,GMF)强度的亚磁场(hypomagnetic field,HMF)(≤5μT),是地外空间的主要环境因素之一,也是研究地磁场生物学功能的必要条件。生物体对亚磁场的感知和响应是生物磁学和空间生命科学领域的基本科学问题之一。本文从氧化应激、能量代谢以及神经内分泌等方面,综述了动物亚磁效应及其生化和分子机制研究的最新进展,同时探讨了多通路介导亚磁生物效应的可能机制。 Hypomagnetic field (HMF),with a magnetic intensity ≤5 μT,which is much lower than that of the geomagnetic field (GMF) intensity (average 50 μT),is a major environmental factor in outer space. Establishment of the hypomagnetic facility is a necessary condition to investigate the biological function of the GMF.The biosensation and response to the HMF is one of the fundamental issues in the field of biomagnetics and space life science.In this paper,we reviewed the progresses in recent studies of biochemical and molecular mechanisms underlying the effects of the HMF on oxidative stress,energetic metabolism and neural endocrine in animals;as well as multiple pathways involving in the bio-HMF effects.
作者 莫炜川 胡平东 樊竹 刘缨 赫荣乔 MO Weichuan;HU Pingdong;FAN Zhu;LIU Ying;HE Rongqiao(State Key Laboratory of Brain and Cognitive Science,Institute of Biophysics,CAS,Beijing 100101,China;School of Life Sciences,Beijing University of Chinese Medicine,Beijing 102488,China;University of Chinese Academy of Sciences,Beijing,100101)
出处 《生命的化学》 CAS CSCD 2019年第5期930-935,共6页 Chemistry of Life
基金 国家自然科学基金项目(31870840)
关键词 亚磁场 生物磁效应 氧化应激 能量代谢 神经递质 动物行为 hypomagnetic field biomagnetic effect oxidative stress energy metabolism neural transmitter animal behavior
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