摘要
随着中药在全球范围内的广泛应用,中药不良反应/不良事件报道不断增加,引发人们对中药安全性问题的广泛关注。该文通过查阅文献,综述中药毒性与中药不良反应相关性和发生机制、中药毒理作用在机体各系统中的表现形式,总结分析近年来常用中药不良反应报道,以期为客观认识中药不良反应、保障临床安全用药提供参考。
With the increasing of worldwide application of Traditional Chinese medicine(TCM), the reports of adverse reactions and events of TCM have been increasing, which cause a widespread concern about the safety of TCM.In this article, the relationship of the toxicity and adverse reactions of TCM and potential mechanism, the manifestation of toxicological effects of TCM in various systems of the body, and the reports of commonly used adverse reactions of TCM in recent years were summarized based on literature research.Moreover, this review aimed to objectively understand the adverse reactions of TCM and provide reference for clinical safety medication.
作者
董世芬
宁一博
靳洪涛
DONG Shifen;NING Yibo;JIN Hongtao(Department of Pharmacology, School of Chinese Medica,Beijing University of Chinese Medicine, Beijing 102488, China;Center for New Drug Safety Evaluation and Research, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100050, China)
出处
《医药导报》
CAS
北大核心
2019年第11期1419-1424,共6页
Herald of Medicine
基金
十三五重大新药创制专项(2018ZX09201017-005
2018ZX09711001-002-001)
关键词
中药不良反应
中药毒性
作用机制
Adverse reactions of traditional Chinese medicine
Toxicity of traditional Chinese medicine
Mechanism of action