依达拉奉注射液处方筛选与工艺研究

Study on prescription and process of Edaravone Injection

〔目的〕研究依达拉奉注射液(Edaravone Injection)处方与工艺。〔方法〕根据依达拉奉性质,通过处方筛选、工艺设计、稳定性试验考察,探究依达拉奉注射液处方工艺。〔结果〕筛选出满足注射剂质量标准的依达拉奉注射液处方及工艺。〔结论〕按所得处方工艺制备依达拉奉注射液,处方设计合理、制备工艺可行、注射剂性质稳定。

〔Objective〕To study the formulation and process of Edaravone Injection.〔Methods〕According to the property of the drug itself, prescription and process of Edaravone Injection are screened by prescription conditions, process conditions and stability tests.〔Results〕The formulation and process of Edaravone Injection are screened to meet the quality requirements of injections.〔Conclusion〕According to the above prescription and the preparation of Edaravone Injection, the prescription is reasonable, the preparation process is feasible and the initial stability is good.