两种核磁靶向穿刺诊断有临床意义前列腺癌精确性的比较

Comparison of two different approaches of MRI-targeted biopsy on the diagnosis of clinically significant prostate cancer

目的比较两种不同方式核磁(MRI)靶向穿刺诊断有临床意义前列腺癌的准确性。方法入组2015~2017年北京和睦家医院45例行认知融合穿刺患者,北京医院87例行MRI引导下穿刺患者,对比两组患者年龄、前列腺特异抗原(PSA)、前列腺体积、前列腺影像报告和数据系统(PI-RADS)评分等临床资料,分析穿刺结果中前列腺癌以及有临床意义前列腺癌的检出率。结果MRI引导穿刺组患者年龄明显高于认知融合穿刺组;而两组患者PSA、前列腺体积、PI-RADS评分差异均无统计学意义。在总体前列腺癌检出率方面,MRI引导穿刺组为52.9%,认知融合穿刺组为31.1%(P<0.05);在有临床意义前列腺癌检出率方面,MRI引导组为29.9%,认知融合穿刺组为20.0%(P>0.05)。结论MRI引导穿刺与认知融合穿刺对于诊断有临床意义前列腺癌精确性都较高,但MRI引导穿刺在总体前列腺癌检出率方面更有优势。

Objective To compare the diagnosis accuracy of clinically signi ficant prostate cancer by two different MRI-targeted biopsy approaches.Methods A total of 45 men from Beijing United Family Hospital undergoing cognitive biopsy and 87 men from Beijing Hospital undergoing in-bore biopsy were included in the study from 2015 to 2017.The patients age,PSA,prostate volume,PI-RADS,overall prostate detection rate and clinically significant prostate cancer detection rate were compared and analyzed.Results The age in in-bore biopsy group was higher than cognitive biopsy group.There was no signi ficant difference in PSA,prostate volume,and distribution of PI-RADS between the two groups.The overall prostate cancer detection rate was 52.9%by in-bore biopsy and 31.1%by cognitive biopsy(P<0.05).The clinically significant prostate cancer detection rate was 29.9%by in-bore biopsy and 20.0%by cognitive biopsy(P>0.05),respectively.Conclusions Both biopsies had good performance in clinically signi ficant prostate cancer detection.But in-bore biopsy showed remarkably higher overall prostate cancer detection rate compared with cognitive biopsy.