近十年重症肌无力的中医病因病机研究概况

Overview of TCM Etiology and Pathogenesis of Myasthenia Gravis in Recent Ten Years

通过收集国内近十年(2008-2018年)中国知网公开发表关于重症肌无力的中医期刊文献,概述近十年有关研究重症肌无力的中医病因病机,以期为今后深入研究提供更多的思路。中医对重症肌无力的研究在病因方面的论述探索不多,在病机方面相对较多较全面,主要病因以风、湿邪及先天禀赋不足、饮食劳逸不节为主,病机以脾肾亏虚、脾胃虚弱较为多见,在病程后期往往夹杂不同程度的湿浊、瘀、毒。其发病与脾、胃、肾、肝关系密切,其中以脾、肾最为关键,正气亏虚是重症肌无力发生的前提,湿浊、瘀、毒是反复不愈、肌肉痿废不用的病理基础。

In order to provide more ideas for further researches, the paper summarized the literatures published on CNKI about the research on the etiology and pathogenesis of myasthenia gravis in past ten years (2008一2018). In recent years, the etiology of myasthenia gravis in traditional Chinese medicine is lack of exploration, while the pathogenesis is relatively more comprehensive. The main etiology is wind, dampness evil and congenital endowment insufficiency, the main pathogenesis is deficiency of spleen and kidney, the weakness of spleen and stomach is more common. And the dampness, stasis and poison of different degree are often mixed in the late stage of the course of disease. The pathogenesis is related to spleen, stomach, kidney and liver, in which spleen and kidney are the key deficiency of qi is the premise of myasthenia gravis. Dampness, stasis and poison are the pathological basis of repeated failure to heal and the wasting of muscle.