卒中后癫痫的预后及其影响因素

Prognosis of poststroke epilepsy and its influencing factors

目的探索卒中后癫痫(PSE)患者的预后及其影响因素。方法收集PSE患者,至少随访2年,以是否达至少1年无发作作为判断预后的标准,将PSE患者分为预后好和预后差两组,通过单因素和多因素Logistic回归分析,比较两组患者的临床特点,分析PSE预后差的危险因素。结果共纳入102例PSE患者,其中59例(57.8%)预后好。单因素Logistic回归分析显示卒中部位累及皮质的患者在预后差组中明显增多,与预后好组相比,差异有统计学意义(P<0.05)。多因素Logistic回归分析显示卒中部位累及皮质是PSE预后差的独立危险因素(OR=7.72, 95%CI:3.11~19.13,P<0.001)。结论 PSE预后较好,卒中部位累及皮质的PSE患者癫痫控制不佳。

Objective To explore the prognosis and influencing factors of patients with poststroke epilepsy(PSE). Methods Patients with PSE were collected and followed up for at least 2 years. Whether they have reached at least 1 year without onset was a criterion to determine prognosis. PSE patients were divided into 2 groups with good prognosis and poor prognosis. Through single factor and multi-factor Logitic regression analysis, the clinical characteristics of the two groups were compared. The risk factors for poor prognosis of PSE were analyzed. Results A total of 102 PSE patients were included, of which 59(57.8%) had a good prognosis. The single factor Logitic regression analysis showed that patients involved in the cortex in the stroke area had a significant increase in the poor prognosis group. The difference was statistically significant compared with the good prognosis group(P<0.05). Multiple factor Logitic regression analysis showed that cortical involvement in stroke site was an independent risk factor for poor prognosis of PSE(OR=7.72, 95%CI: 3.11-19.13, P<0.001). Conclusion The prognosis of PSE patients is favorable, but a poor control can be seen in the patients with cerebral cortex.