药学干预在促进中药注射剂使用合理性中的作用观察

Observation on the role of pharmaceutical intervention in promoting the rational use of traditional Chinese medicine injection

目的探究药学干预在促进中药注射剂使用合理性中的效果.方法选取2018年3~8月230例使用中药注射剂患者作为对照组,未采用药学干预;选取2018年9月~2019年2月250例使用中药注射剂患者作为干预组,采用药学干预.比较两组中药注射剂使用情况、用药合理性、住院时间、治疗费用及不良反应发生情况.结果对照组使用前十的中药注射剂中,除热毒宁注射液用量和金额上升外,其余9种中药注射剂在干预组中均出现了用量和金额的显著下滑.两组患者中药注射剂涉及活血、抗肿瘤、清热、补益4类30个品种.干预组患者用药合理率为96.8%(242/250),高于对照组的91.3%(210/230),差异具有统计学意义(P<0.05).干预组患者不良反应发生率低于对照组,差异具有统计学意义(P<0.05).干预组患者治疗费用低于对照组,住院时间短于对照组,差异均有统计学意义(P<0.05).结论实施药学干预可以强化临床医师合理应用中药注射剂的意识,提高合理用药水平,减少不良反应的发生,降低治疗费用.

Objective To investigate the effect of pharmaceutical intervention in promoting the rational use of traditional Chinese medicine injection. Methods There were 230 patients who used traditional Chinese medicine injection from March to August 2018 selected as control group, and received no pharmaceutical intervention;250 patients who used traditional Chinese medicine injection from September 2018 to February 2019 were selected as intervention group, and received pharmaceutical intervention. Comparison was made on use of traditional Chinese medicine injection, rationality of drug use, hospitalization time, treatment cost and occurrence of adverse reactions between the two groups. Results Among the top 10 Chinese medicine injections used in the control group, the dosage and costs of 9 kinds of traditional Chinese medicine injections decreased significantly in the intervention group except for the increase of the dosage and costs of Reduning injection. The traditional Chinese medicine injection involved blood, anti-cancer, heat, tonic four categories of 30 varieties in two groups. The rational rate of drug use was 96.8%(242/250) in the intervention group, and that was higher than 91.3%(210/230) in the control group, and the difference was statistically significant(P<0.05). The incidence of adverse reactions in the intervention group was lower than that in the control group, and the difference was statistically significant(P<0.05). The treatment costs in the intervention group was lower than that in the control group, and the hospitalization time was shorter than that in the control group. Their difference was statistically significant(P<0.05). Conclusion Pharmaceutical intervention can strengthen clinicians’ awareness of rational use of traditional Chinese medicine injections, improve the level of rational use of drugs, reduce the occurrence of adverse reactions and reduce the treatment cost.