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糖尿病合并非酒精性脂肪性肝病患者血清Betatrophin 水平与脂代谢相关指标相关性分析 被引量:4

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摘要 目的考察糖尿病合并非酒精性脂肪性肝病患者血清Betatrophin水平及其与脂代谢相关指标的相关性。方法选取56例糖尿病合并NAFLD患者作为观察组,同时选取56例单纯糖尿病患者作为对照组,比较两组患者血清Betatrophin水平、脂代谢和糖代谢相关指标,并对代谢指标与Betatrophin水平关系进行分析。结果观察组患者血清Betatrophin水平显著高于对照组(P<0.05)。观察组患者甘油三酯、总胆固醇和低密度脂蛋白水平显著高于对照组(P<0.05),高密度脂蛋白水平显著低于对照组(P<0.05)。观察组患者糖化血红蛋白水平显著高于对照组(P<0.05),其他糖代谢指标差异无统计学意义(P>0.05)。观察组患者血清Betatrophin水平与空腹血糖、糖化血红蛋白水平、甘油三酯、总胆固醇和低密度脂蛋白水平正相关,与高密度脂蛋白和HOMA-β指数负相关(P<0.05)。结论糖尿病合并脂肪肝患者血清Betatrophin水平较高且是反映患者血脂水平的有效参考因素。
作者 何宝明
出处 《肝脏》 2019年第10期1168-1170,共3页 Chinese Hepatology
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