摘要
在女性恶性肿瘤中乳腺癌的发病率居首位,具有发病率高、根治性差的特点。肿瘤干细胞与正常干细胞一样,具有不可控制的繁殖能力和不断自我更新完善的能力,有研究认为肿瘤干细胞在肿瘤的发生、复发以及转移中起到一定的作用,对乳腺癌肿瘤干细胞及表面标志物进行研究,可以帮助人们从根本上认识乳腺癌的发病机制,并从机制入手寻求治疗的方法和预防的手段。相信随着科研的深入,针对乳腺癌肿瘤干细胞的治疗,必然会为广大乳腺癌患者带来福音。
In malignant tumors,the incidence of breast carcinoma in female is the first with a high incidence and poor curerate. Like normal stem cells,tumor stem cells have an uncontrollable ability to reproduce and constantly renew themselves. Some studies suggest that tumor stem cells play a certain role in the occurrence,recurrence and metastasis of tumors.Studying the tumor stem cells and its surface markers can help to understand the pathogenesis of breast carcinoma,as a result can cure or prevent breast cancer. With the progress of scientific research,the treatment targeting breast cancer stem cells will inevitably bring good results to the patients.
作者
周飞
乔娜
马爽
齐天源
张静
李锐
ZHOU Fei;QIAO Na;MA Shuang;QI Tianyuan;ZHANG Jing;LI Rui(Ward Two of Breast Surgery,Qiqihar First Hospital,Qiqihar 161005,China;Department of Clinical Medicine,the Second Affiliated Hospital of Harbin Medical University,Harbin 150081,China)
出处
《医学综述》
2019年第20期4014-4018,共5页
Medical Recapitulate
基金
黑龙江省博士后科研启动金(LBH-Q17176)
齐齐哈尔市科技局指导项目(SFZD-2019038)
关键词
乳腺癌
肿瘤干细胞
乳腺癌肿瘤干细胞
表面标志物
治疗应用
Breast cancer
Cancer stem cells
Cancer stem cells of breast cancer
Surface markers
Therapeutic application