手术治疗无骨折脱位的颈椎后纵韧带骨化症预后相关因素的研究进展

Prognostic Factors for Surgical Outcome in Cervical Ossification of Posterior Longitudinal Ligament without Fracture and Dislocation

颈椎后纵韧带骨化症(OPLL)是后纵韧带的异常骨化,可导致椎管狭窄和脊髓、神经根压迫,最终引起神经功能障碍。颈椎OPLL的治疗包括保守治疗和手术治疗,保守治疗包括物理治疗和药物治疗等;而严重的颈椎OPLL需要手术治疗,解除脊髓压迫,改善患者症状,防止患者症状进一步加重。通过影像学检查以及其他检查可对患者进行术前评估,判断预后,选择合适的手术方式和防止术中、术后并发症,从而改善患者预后。影响颈椎OPLL的预后因素较多,如术前的神经功能状态、脊髓压迫比率、磁共振成像的脊髓信号强度等级等。

Cervical ossification of the posterior longitudinal ligament( OPLL) is the abnormal ossification of the posterior longitudinal ligament,which can cause spinal stenosis,compression of the spinal cord,compression of nerve root and finally neurologic dysfunction. Treatments of cervical OPLL include conservative treatments and surgical treatments. Conservative treatments include physiotherapy and drug therapy. Severe cervical OPLL should be treated by surgery to decompress the spinal cord,improve the symptoms and prevent from progression. Preoperative evaluation of patients is conducted through imaging examination and other examinations to judge the prognosis and select appropriate surgical methods and prevent intraoperative and postoperative complications,so as to improve the prognosis. There are many prognostic factors associated with surgical outcomes of cervical OPLL,such as preoperative neurological status,cord compression ratio,and MRI signal intensity grade etc.