早产儿与足月儿新生儿败血症临床特点对比研究

Comparative Study of Clinical Features of Neonatal Sepsis in Preterm and Term Infants

目的探讨早产儿与足月儿新生儿败血症临床特点对比研究。方法选择2016 年1 月—2018 年5 月本院收治的新生儿败血症患者80例,按照出生孕周分为早产儿组与足月儿组,均为40 例。比较发病相关因素、住院期间临床表现及治疗期间出现的相关并发症。结果足月儿组发病因素中羊水污染比例显著多于早产儿组(P < 0.05),而胎膜早破及母体感染比例显著低于早产儿组(P < 0.05),足月儿组其体温显著高于早产儿组(P < 0.05),出生3 天血清胆红素值指数低于早产儿组(P < 0.05),新生儿组出现肺炎、颅内出血、脑膜炎的比例显著低于早产儿组(P < 0.05)。结论足月新生儿体温显著升高,同时合并羊水污染及胎儿宫内窘迫,早产儿早期黄疸明显升高,同时合并胎膜早破及母体感染者,应引起临床重视,及时排除新生败血症的发生。

Objective To investigate the clinical features of neonatal sepsis in preterm infants and term infants. Methods 80 neonatal sepsis patients admitted to our hospital from January 2016 to May 2018 were selected and divided into preterm infants and full-term infants according to their gestational age. All patients were 40 patients. The incidence-related factors, clinical manifestations during hospitalization, and related complications during treatment were compared. Results The incidence of amniotic fluid contamination were significantly more than those in preterm infants (P<0.05). The proportion of premature rupture of membranes and maternal infection was significantly lower in preterm infants than in preterm infants (P<0.05). The body temperature of month group was significantly higher than that of preterm group (P<0.05). The serum bilirubin value index at 3 days of birth was lower than that of preterm infants (P<0.05).The incidence of pneumonia, intracranial hemorrhage and meningitis was significantly lower in the neonate group. Preterm infants group (P<0.05). Conclusion The body temperature of full-term neonates is significantly elevated, combined with amniotic fluid contamination and fetal distress in the fetus. Early jaundice in preterm infants is significantly elevated. Premature rupture of fetal membranes and maternal infection should be given attention to, and the occurrence of neonatal sepsis should be ruled out in time.