肺康复联合呼吸机治疗AECOPD合并呼吸衰竭的效果

Effect of Pulmonary Rehabilitation Combined With Ventilator on AECOPD Combined With Respiratory Failure

目的探索肺康复联合无创呼吸机治疗慢性阻塞性肺疾病急性加重(AECOPD)合并呼吸衰竭的有效性。方法纳入120例符合纳入标准的AECOPD 患者,随机分为无创呼吸机+肺康复治疗组和无创呼吸机治疗组,分析两组间治疗及预后信息。结果本研究纳入患者主要为吸烟男性患者,大部分患者为GOLD Ⅱ级。肺康复联合无创呼吸机治疗可显著缩短患者住院期间无创呼吸机使用时间(P =0.011)、平均住院日(P =0.006),但两组间因初始治疗失败需气管插管、48h 后动脉血气分析主要结果之间差异无统计学意义。结论肺康复联合无创呼吸机治疗AECOPD 患者可显著减少缩短呼吸机使用时间、住院时间,且不会增加患者氧和下降、气管插管风险等。

Objective th non-invasive ventilator in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with respiratory failure. Methods A total of 120 AECOPD patients who met the inclusion criteria were randomly divided into non-invasive ventilator + pulmonary rehabilitation group and non-invasive ventilator treatment group. The treatment and prognosis information between the two groups were analyzed. Results The study included patients with predominantly smoking males, most of whom were of GOLD Ⅱ. Pulmonary rehabilitation combined with non-invasive ventilator treatment can significantly shorten the use of non-invasive ventilator during hospitalization (P=0.011) and average hospitalization days (P=0.006), but the initial treatment failure requires tracheal intubation, 48h post-arterial blood gas No significant statistical differences were found between the main results of the analysis. Conclusion Pulmonary rehabilitation combined with non-invasive ventilator in patients with AECOPD can significantly reduce the use of ventilator, hospital stay and does not increase the risk of oxygen and decline in patients, endotracheal intubation.