CRISPR/Cas9基因编辑技术研究进展

A Research progress of CRISPR/Cas9 Gene Editing Technology

人类基因组计划完成后,如何在活体细胞,特别是哺乳动物细胞中实现对遗传信息的精确编辑是分子生物学领域研究的热点。2013年,科学家们相继证实CRISPR/Cas9技术可以在活细胞、哺乳动物和其他生物基因组中实现对遗传信息的靶向编辑,从此该技术迅速席卷全球。基于此,本文简要阐述CRISPR/Cas9基因编辑技术的诞生和发展过程,以期促进社会对基因编辑工作的理解和支持。

After the completion of the human genome project, how to accurately edit genetic information in living cells, especially mammalian cells is a hot topic in the field of molecular biology.In 2013, scientists have confirmed that CRISPR/ Cas9 technology can achieve targeted editing of genetic information in living cells, mammals and other biological genomes, and the technology has swept the world rapidly.This article will briefly describe the birth and development of CRISPR/Cas9 gene editing technology, with a view to promoting social understanding and support for scientific research.