伐他汀联合阿司匹林治疗脑血栓的效果及对神经功能缺损的影响价值体会

The effect of simvastatin combined with aspirin on cerebral thrombosis and its value in neurological deficit

目的探索辛伐他汀联合阿司匹林治疗脑血栓恢复期的效果及对神经功能缺损的影响性。方法选取2017年4月22日至2018年4月22日期间我院脑血栓恢复期100例患者(实施基数偶数法分组模式),对照组的50例患者进行阿司匹林治疗,观察组的50例患者进行辛伐他汀联合阿司匹林治疗。结果观察组患者的Barthel指数(94.13±2.13)分、NIHSS评分(4.81±1.41)分、LDL-C(2.43±0.56)mmol/L、HDL-C(1.85±0.33)mmol/L、TC(1.25±0.03)mmol/L、TG(5.11±0.07)mmol/L、斑块面积(1.22±0.03)cm^2、IMT(0.23±0.06)mm均优于对照组(P<0.05)。结论对脑血栓恢复期患者实施辛伐他汀联合阿司匹林治疗效果明显,可改善神经功能缺损。

Objective To explore the effect of simvastatin combined with aspirin on the recovery of cerebral thrombosis and its influence on neurological deficits.Methods 100 patients with cerebral thrombosis in our hospital from April 22,2017 to April 22,2018 were enrolled in the hospital.The 50 patients in the control group were treated with aspirin and 50 patients in the observation group.The patient was treated with simvastatin in combination with aspirin.Results Barthel index(94.13±2.13),NIHSS score(4.81±1.41),LDL-C(2.43±0.56)mmol/L,HDL-C(1.85±0.33)mmol/L,TC(in patients).(1.25±0.03)mmol/L,TG(5.11±0.07)mmol/L,plaque area(1.22±0.03)cm^2,IMT(0.23±0.06)mm were superior to the control group(P<0.05).Conclusion The treatment of cerebral thrombosis in patients with simvastatin combined with aspirin is effective,which can improve neurological deficits.