音乐电刺激治疗功能性消化不良的临床研究

Clinical study of music electrical stimulation in treatment of functional dyspepsia

目的观察音乐电刺激治疗功能性消化不良的临床疗效。方法选取符合罗马Ⅲ诊断标准的功能性消化不良患者81例,按随机数字表法分为治疗组(41例)和对照组(40例)。对照组给予口服泮托拉唑肠溶胶囊及枸橼酸莫沙必利片;治疗组在口服药物基础上给予音乐电刺激治疗;治疗4周后观察疗效。两组患者治疗前后均评价主要症状积分、抑郁自评量表(SDS)、焦虑自评量表(SAS)得分以及记录餐前后体表胃电图(EGG)。结果在症状、疗效评价上,治疗组总有效率达85.36%,优于对照组的67.50%(P<0.05);与治疗前相比,治疗组的SDS、SAS评分明显降低(P<0.05),对照组SDA、SAS评分无明显改变;治疗组治疗后EGG主频率、餐后/餐前主功率较治疗前明显改善(P<0.01),对照组则改善不明显。结论音乐电刺激治疗可以改善消化不良症状、焦虑抑郁状态,调节胃电节律紊乱和增强胃电功率。

Objective To observe the clinical efficacy of music electrical stimulation in the treatment of functional dyspepsia. Methods Eighty-one patients meeting the Roman Ⅲ diagnostic criteria of functional dyspepsia were selected and randomly divided into the treatment group ( n =41) and control group ( n =40) according to the ramdon number table method.The control group was given oral Pantoprazole Enteric Capsule and Mosapride Citrate Tablets,and the treatment group was treated with music electric stimulation on the basis of oral medication.After 4-week treatment,the curative effect was observed.were evaluated before and after treatment in the two groups. Results In the evaluation of symptomatic curative effect,the total effective rate of the treatment group reached 85.36%,which was superior to 67.50% in the control group;the SDS and SAS scores in the treatment group were significantly decreased compared with those before treatment ( P < 0.05 ),while which in the control group had no obvious change;the dominant frequency of surface electrocardiogram (EGG) and the dominant power after meal /before meal after treatment in the treatment group were significantly improved compared with before treatment ( P <0.01),while which in the control group had no obvious change. Conclusion The music electrical stimulation treatment can improve the dyspepsia symptoms,anxiety and depression state,regulate gastric electrical rhythm disorders and enhance gastric electrical power.