维生素A在早产儿支气管肺发育不良预防中的研究进展

Study progress of vitamin A in prevention of bronchopulmonary dysplasia among premature infants

维生素A(VA)是机体重要的脂溶性维生素,能维持正常视觉、上皮完整、免疫功能,促进生长发育及增强机体抗感染能力。支气管肺发育不良(BPD)是一种慢性肺部疾病,近年随着早产儿存活率显著提高,BPD发生率也呈升高趋势,VA在早产儿肺发育的应用逐渐通过动物实验及临床被认识,现主要就VA在早产儿BPD预防中的相关内容进行综述。

Vitamin A (VA) is an important fat-soluble vitamin of the body ,which can maintain normal vision,epithelial integrity and immune function,promote the growth and development,and enhance the body′s anti-infection ability.Bronchopulmonary dysplasia (BPD) is a chronic lung disease.In recent years,with the survival rate of premature infants significantly increasing,the incidence rate of BPD also show the increasing trend.The application of VA in premature infant′s lung development is gradually recognized through animal experiments and clinical practice.This article reviews the related contents of VA in the prevention of BPD among premature infants.