一例多重耐药鲍曼不动杆菌血流感染药物治疗方案探讨

Treatment strategies of a patient with bloodstream infection of multi-drug resistant Acinetobacter baumannii

目的:通过探讨1例多重耐药鲍曼不动杆菌血流感染治疗成功的抗感染治疗策略,为复杂性感染病例优化治疗积累经验。方法:临床药师参与1例多重耐药鲍曼不动杆菌血流感染老年患者的治疗。根据自身专业特点并紧密结合患者实际病情,参与制订抗感染治疗方案,根据血药浓度调整药物的剂量,协助临床医师进一步优化抗感染药物治疗方案。结果:患者感染得到有效控制,未出现药物相关不良反应。结论:临床药师作为临床团队一员,应充分运用药学知识参与制订合理的治疗方案,并观察药物疗效,监测不良反应,保证药物治疗安全、有效、经济。

Objective:To discuss anti-infection strategies through successful treatment of a patient with bloodstream infection of multi-drug resistant Acinetobacter baumannii,and to accumulate clinical experience for the treatment of complicated infection cases.Methods:Clinical pharmacists participated in the treatment of an elderly patient with bloodstream infection of multi-drug resistant Acinetobacter baumannii.Based on the professional characteristics and closely combined with the actual conditions of the patient,clinical pharmacists were involved in the development of anti-infection strategies and adjustment of drug dosage according to blood drug concentrations,and assisted clinicians to further optimize anti-infection strategies.Results:The infection in the patient was effectively controlled,and no adverse drug reactions occurred.Conclusion:As a member of the clinical team,clinical pharmacists should make full use of their pharmaceutical knowledge in the development of therapeutic regimen,observe the efficacy and monitor adverse drug reactions,so as to insure safety,efficiency and economy of drug treatment.