293例2～6个月婴儿听性脑干反应结果分析

Analysis of Auditory Brainstem Responses in 293 infants Aged 2～6 Months

目的:探讨听力正常2~6月龄婴儿短声听性脑干反应(click-evoked auditory brainstem response,c-ABR)的Ⅰ、Ⅲ、Ⅴ波潜伏期及波间期的正常参考值范围。方法:对293例听力正常2~6月龄婴儿的80 dB nHL短声听性脑干反应Ⅰ波、Ⅲ波、Ⅴ波潜伏期及Ⅰ~Ⅲ、Ⅲ~Ⅴ、Ⅰ~Ⅴ波间期的数据进行统计分析。结果:波Ⅰ、Ⅲ、Ⅴ的潜伏期及Ⅰ~Ⅲ、Ⅲ~Ⅴ、Ⅰ~Ⅴ波间期均随月龄的增大而缩短,男婴及女婴的波Ⅲ、Ⅴ潜伏期和男婴的Ⅰ~Ⅲ、Ⅲ~Ⅴ、Ⅰ~Ⅴ波间期在不同月龄之间的差异有统计学意义,而女婴的Ⅰ~Ⅲ、Ⅲ~Ⅴ、Ⅰ~Ⅴ波间期在不同月龄之间的差异无统计学意义;在同月龄段中,女婴波Ⅲ、Ⅴ的潜伏期及Ⅰ~Ⅲ、Ⅰ~Ⅴ波间期均比男婴短,差异有统计学意义。结论:确定小婴儿不同年龄段、不同性别的ABR正常值参考范围,可有效减少漏诊、误诊。

Objective:To investigate the normal range of reference values of waveⅠ,Ⅲ,Ⅴand inter-wave period of auditory brainstem responses(ABR)in Infants aged 2~6 months.Methods:Tested 293 cases of infants Aged 2~6 Months whose hearing comprehensive assessment in normal range,statistical analysis the latency of waveⅠ,Ⅲ,Ⅴand inter-wave period of 80 dB nHL,c-ABR.Results:The latency of waveⅠ,Ⅲ,Ⅴand inter-wave period ofⅠ~Ⅲ,Ⅲ~Ⅴ,Ⅰ~Ⅴwere shortened with the increase of age,the difference of the infant's waveⅢ,Ⅴlatency and inter-wave period ofⅠ~Ⅲ,Ⅲ~Ⅴ,Ⅰ~Ⅴin male group between different months was statistically significant,but there was no significant difference in inter-wave period ofⅠ~Ⅲ,Ⅲ~Ⅴ,Ⅰ~Ⅴof the female group between different months.The female babies'latency of waveⅢ,Ⅴand inter-wave period ofⅠ~Ⅲ,Ⅰ~Ⅴwere shorter than that of the male babies',and this difference was statistically significant.Conclusions:In order to use the ABR better clinically,establishing the reference range of normal in different age and sex for infants is suggested.