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肾炎舒胶囊+厄贝沙坦治疗早期糖尿病肾病的临床疗效及对患者血清炎症因子水平的影响

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摘要 目的观察肾炎舒胶囊+厄贝沙坦治疗早期糖尿病肾病的临床疗效及对患者血清炎症因子水平的影响。方法 82例早期糖尿病肾病患者,根据治疗方式不同分为对照组和试验组,每组41例。两组患者均接受糖尿病基础治疗,在此基础上,对照组接受厄贝沙坦治疗,试验组则给予厄贝沙坦联合肾炎舒胶囊治疗。比较两组患者临床疗效及治疗前后血清炎症因子[白细胞介素6(IL-6)、超敏C反应蛋白(hs-CRP)]水平。结果试验组患者的临床总有效率92.68%显著高于对照组的73.17%,差异具有统计学意义(P<0.05)。治疗前,两组患者的IL-6、hs-CRP水平比较,差异均无统计学意义(P>0.05);治疗后,两组患者的IL-6、hs-CRP水平均低于治疗前,且试验组低于对照组,差异均具有统计学意义(P<0.05)。结论在早期糖尿病肾病患者治疗中,肾炎舒胶囊联合厄贝沙坦治疗更利于患者病情恢复,且可调节血清炎症因子水平,较单纯给药治疗效果更为理想,值得借鉴。
作者 张艳
出处 《中国现代药物应用》 2019年第20期79-80,共2页 Chinese Journal of Modern Drug Application
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