甲基多巴联合硝苯地平治疗妊娠期高血压疾病42例效果观察

Effect of Methyldopa Combined Nifedipine in 42 Cases of Hypertensive Disorder Complicating Pregnancy

目的:探究妊娠期高血压疾病患者应用甲基多巴联合硝苯地平治疗的效果。方法:将2017年1月-2018年12月笔者所在医院收治的84例妊娠期高血压疾病的患者纳入研究范围,并应用随机数字表法进行平均分组,试验组应用甲基多巴联合硝苯地平进治疗,对照组单纯甲基多巴治疗,对比临床治疗效果。结果:试验组患者治疗的总有效率显著高于对照组,且试验组患者新生儿窒息、胎盘早剥、产后出血及胎儿宫内窘迫等不良分娩结局发生率显著低于对照组,差异均有统计学意义(P<0.05)。结论:采用甲基多巴联合硝苯地平对妊娠期高血压疾病患者进行干预,有利于稳定患者的血压水平,降低不良分娩情况的发生率。

Objective: To explore the effect of Methyldopa and Nifedipine on patients with hypertensive disorder complicating pregnancy. Method: A total of 84 patients with hypertensive disorder complicating pregnancy in our hospital from January 2017 to December 2018 were enrolled in the study. The patients were divided into two groups by means of random number table. The experimental group treated by Methyldopa combined with Nifedipine and the control group by Methyldopa alone.The clinical effects were compared between the two groups. Result: The total effective rate of the experimental group was significantly higher than that of the control group, and the incidence of adverse delivery outcomes such as neonatal asphyxia, placental abruption, postpartum hemorrhage and fetal distress in the experimental group was significantly lower than that in the control group, the differences were statistically significant (P<0.05). Conclusion: The intervention of Methyldopa combined with Nifedipine in patients with hypertensive disorder complicating pregnancy is helpful to stabilize the blood pressure level of patients and reduce the incidence of adverse delivery outcomes.