红细胞分布宽度及超敏C反应蛋白对急性脑梗死预后的影响

Effect of Red Blood Cell Distribution Width and Hypersensitive C-reactive Protein on Prognosis of Acute Cerebral Infarction

目的:探讨红细胞分布宽度(RDW)及超敏C反应蛋白(hs-CRP)对急性脑梗死预后的影响。方法:将2018年1月-2019年6月笔者所在医院收治的164例急性脑梗死患者作为研究对象,根据改良Rankin量表(modified Rankin scale,mRS)评分标准进行分组,mRS≤2分即为预后良好组(101例),mRS>2分即为预后不良组(63例)。进行单因素分析及多因素Logistic回归分析患者预后的影响因素。结果:单因素分析显示,预后良好组患者NIHSS评分、高脂血症率、糖尿病率、RDW值、hs-CRP水平均低于预后不良组(P<0.05);多因素分析显示,入院NIHSS评分、RDW升高、hs-CRP水平增加均为影响急性脑梗死患者预后的独立危险因素(P<0.05)。结论:急性脑梗死患者RDW及hs-CRP水平对患者预后具有重要的临床价值。

Objective:To investigate the effect of red blood cell distribution width(RDW)and hypersensitive C-reactive protein(hs-CRP)on the prognosis of acute cerebral infarction.Method:A total of 164 patients with acute cerebral infarction admitted in our hospital from January 2018 to June 2019 were selected as the clinical research objects.According to the modified Rankin scale(mRS)score standard,the patients with mRS≤2 points were classified as the group with good prognosis(101 cases),and the patients with mRS>2 points were classified as the group with poor prognosis(63 cases).Univariate analysis and multivariate Logistic regression were used to analyze the influencing factors of prognosis.Result:Univariate analysis showed that NIHSS score,hyperlipidemia rate,diabetes rate,RDW value and hs-CRP level in the group with good prognosis were all lower than those in the group with poor prognosis(P<0.05).Multivariate analysis showed that NIHSS score,increased RDW and increased hs-CRP level were all independent risk factors affecting the prognosis of patients with acute cerebral infarction(P<0.05).Conclusion:RDW and hs-CRP levels in patients with acute cerebral infarction have important clinical value for prognosis.