多学科合作运动疗法对维持性血液透析患者生活质量及微炎症状态的影响

Effects of multidisciplinary cooperating exercise on quality of life and micro-inflammatory state among patients undergoing Maintenance Hemodialysis

目的:观察多学科合作的运动疗法对血液透析患者生活质量及微炎症状态的影响。方法:采用随机数字表法将符合纳入条件的维持性血液透析患者分为对照组(n=45)和实验组(n=42);对照组不采取任何运动的干预,实验组采用多学科合作的运动疗法,使用智能运动车进行每周3次透析中个性化的渐进式运动干预,共持续12周;观察两组患者干预前后生活质量及微炎症状态的变化。结果:干预12周后,实验组的生活质量SF-36评分高于对照组(P<0.05),超敏C反应蛋白(hs-CRP)和白细胞介素-6(IL-6)值均低于对照组(P<0.05)。结论:基于多学科合作的运动疗法能够提高维持性血液透析患者的生活质量,有效改善患者的微炎症状态,可以作为维持性血液透析患者常规的治疗方法。

Objective: To evaluate the effect of multidisciplinary cooperating exercise on quality of life and microinflammatory state among patients undergoing Maintenance Hemodialysis (MHD). Methods: MHD patients consistent with inclusion criteria were randomly divided into the controls group (n=45) and the experimental group (n=42). Patients in the control group did not take any exercise intervention, while the experimental group conducted multidisciplinary cooperating exercise using smart sports bike three times a week, lasting for 12 weeks. The quality of life and micro-inflammatory state of two groups before and after intervention were assessed and compared. Results: After the intervention, the quality of life of the experimental group was higher than that of the control group (P<0.05). The scores of hypersensitive-C-reactive protein and interleukin-6 of the experimental group were lower than those in the control group (P<0.05). Conclusion: The multidisciplinary cooperating exercise could improve the quality of life and micro-inflammatory state in MHD patients, therefore it can be used as a routine treatment.