人工全膝关节置换术后感染的危险因素分析

Analysis of risk factors of infection after total knee arthroplasty

目的分析人工全膝关节置换术后发生感染的危险因素,为临床预防术后感染提供依据。方法选择2010年1月至2015年1月郑州大学第一附属医院行全膝关节置换术后发生感染的患者46例,统计患者性别、年龄、糖尿病、高血压病、痛风、关节腔注射史、单双侧、心肌梗死、身体其他部位炎症、体质指数(BMI)等数据,采用Logistic多因素回归分析方法对患者感染原因进行分析。结果糖尿病(P<0.05)、心肌梗死(P<0.05)、身体其他部位炎症(P<0.05)、BMI>30kg/m^2(P<0.05)是膝关节置换术后发生感染的高危因素。结论患者术前应仔细询问病史,做好筛查工作,对合并糖尿病、心肌梗死、身体其他部位炎症以及肥胖的患者围术期重点管理,预防感染。

Objective To analyze the risk factors of infection after knee arthroplasty. Methods Forty-six cases of infection after total knee arthroplasty in the First Affiliated Hospital of Zhengzhou University from January 2010 to January 2015 were selected as the study group. The date of gender, age, diabetes mellitus, hypertension, gout, articular cavity injection history, unilateral or bilateral leisons, myocardial infarction, inflammation of other parts of the body, body mass index (BMI) were collected. Conditional logistic multi-factor regression analysis method was used to analyze the causes of infection in patients. Results Diabetes mellitus, myocardial infarction, inflammation of other parts of the body, body mass index>30 kg/m^2 were high risk factors of the infection after total knee replacement (P<0.05). Conclusions Patients with diabetes mellitus, myocardial infarction, inflammation in other parts of the body and obesity should be carefully examined before operation to prevent infection.