舒芬太尼与芬太尼椎管内用药应用于分娩镇痛的效果比较

Comparison of the effects of sufentanil and fentanyl intraspinal administration on labor analgesia

目的探讨舒芬太尼、芬太尼椎管内用药应用于分娩镇痛的效果。方法选取2017年11月至2018年5月待产妇88例为研究对象,根据产妇入院先后顺序编号,并将其随机分为对照组与观察组,每组44例。对照组应用芬太尼,观察组应用舒芬太尼,比较两组镇痛效果、产妇满意度。结果观察组产妇在用药后5 min、1.5 h时期VAS评分显著低于对照组(P<0.05),在0.5 h时两组比较差异未见统计学意义(P>0.05)。观察组患者首次加药时间明显长于对照组(P<0.05),观察组产妇镇痛满意度明显高于对照组(P<0.05)。结论与芬太尼比较,舒芬太尼实施腰硬联合麻醉镇痛效果更佳,产妇对镇痛效果满意度更高,该药物可在临床分娩镇痛中推广使用。

Objective To investigate the effects of sufentanil and fentanyl intraspinal administration on labor analgesia. Methods A total of 88 pregnant women from November 2017 to May 2018 were selected as subjects. They were numbered according to the order of maternal admission and randomly divided into control group and observation group, with 44 cases in each group. The control group was given fentanyl and the observation group was given sufentanil. The analgesic effect and maternal satisfaction were compared between the two groups. Results The VAS scores of the observation group were significantly lower than those of the control group at 5 min and 1.5 h after treatment(P<0.05). There was no significant difference in VAS score between the two groups at 0.5 h(P>0.05). The first dosing time of the observation group was significantly longer than that of the control group(P<0.05). The satisfaction of maternal analgesia in the observation group was significantly higher than that of the control group(P<0.05). Conclusions Compared with fentanyl, sufentanil has better analgesic effect of combined spinal and epidural anesthesia, and maternal satisfaction with analgesic effect is higher. The drug can be promoted in clinical labor analgesia.