全身及局部因素对种植体周围稳态的影响

Effects of systemic and local factors on microbial homeostasis around implants

牙种植术是牙缺失的常规治疗方案。随着种植失败病例的逐年增加,导致种植失败的最主要因素--种植体周围炎逐渐成为专家学者研究的焦点。种植体周围炎与多种因素如吸烟、喝酒、糖尿病、牙周炎、雌激素缺乏、口腔卫生及种植牙修复方式等关系密切。随着"人类微生物组计划"等项目的开展,研究逐渐聚焦于微生物在全身及局部因素中的作用。本文从种植体周围微生物群落稳态研究进展入手,阐述全身及局部因素对种植体周围稳态的影响。

Dental implantation is a routine treatment for tooth loss. With the increasing number of cases of planting failure, the main factor, peri-implantitis, has become the focus of experts and scholars. We recently found that certain systemic and local factors, such as smoking, drinking, diabetes, periodontitis, estrogen deficiency, oral hygiene, and cemented prostheses, may be involved in the occurrence, development, and prognosis of this disease. The Human Microbiome Project and other metagenomic projects worldwide have advanced our knowledge of the human oral microbiota, and the focus on the microbiology change of implants has gradually increased. We aimed to determine the influence of oral microbiota on the occurrence, development, and prognosis of peri-implant diseases by reviewing the recent research progress on peri-implant disease-related oral and systemic diseases.