血清同型半胱氨酸水平与老年抑郁症的相关性

THE CORRELATION BETWEEN SERUM HOMOCYSTEINE LEVEL AND SENILE DEPRESSION

目的 探讨老年抑郁程度与血清HCY水平的相关性。方法 选择60例老年抑郁症患者作为研究组,另选60例健康老年人为对照组。检测两组血清HCY含量,研究组进行HDMD评分,分析抑郁程度与HCY的关系。结果 研究组HCY含量为(14.73±6.27)μmol/L,对照组为(4.84±1.22)μmol/L,两组比较有统计学意义(t=11.99,P<0.01)。随抑郁程度的加重,其血清Hcy水平呈升高趋势(F=30.03,P<0.01)。结论 血清HCY水平能反映老年抑郁程度的变化。

To investigate the relationship between the levels of depression and serum HCY in the elderly. Methods Sixty elderly patients with depression were selected as the study group, and 60 healthy elderly patients were selected as the control group. Serum HCY levels were measured in the two groups. The study group underwent HDMD scores to analyze the relationship between depression and HCY. Results The HCY content of the study group was (14.73±6.27)μmol/L, and that of the control group was (4.84±1.22)μmol/L. The two groups were statistically significant ( t =11.99, P <0.01). With the aggravation of depression, serum Hcy levels increased ( F =30.03, P <0.01). Conclusion Serum HCY levels can reflect changes in the depression levels in the elderly.