右美托咪定在剖宫产术麻醉与分娩镇痛中的研究进展

Research progress of dexmedetomidine in anesthesia and labor analgesia of cesarean section

右美托咪定(DEX)是一种高选择性α2肾上腺素受体激动剂,近年已在剖宫产术麻醉与分娩镇痛中广泛应用。临床研究结果证实,DEX在剖宫产术分娩中具有独特优势,如改善剖宫产术中麻醉及术后镇痛效果,有效预防和治疗剖宫产术中寒战、牵拉反应和宫缩剂所致不良反应,维持血流动力学稳定,以及提高分娩镇痛效果。笔者拟就DEX在剖宫产术麻醉与分娩镇痛中的研究进展进行阐述。

Dexmedetomidine (DEX) is a highly selective α 2 adrenoceptor agonist, which has been widely used in cesarean section anesthesia and labor analgesia in recent years. Recent clinical research results have proved that DEX has unique advantages in cesarean delivery, such as improving the analgesic effect during and after cesarean section, effectively preventing and treating chills, traction reactions and adverse reactions caused by uterine contractions during cesarean section, maintaining hemodynamic stability, and improving labor analgesic effect. The author intends to elaborate the research progress of DEX in cesarean section anesthesia and labor analgesia.