食品质量安全非靶向筛查技术研究进展

Research Development of Non-Targeted Screening Techniques for Food Quality Safety

食品中存在的污染物部分是已知的,部分是未知的。为确保食品质量安全,非针对性的筛查技术是必要的。非靶向筛查主要有两种分析策略,包括非靶向代谢组学和可以用于筛选食品基质中未知污染物的化学数据库。本文概述了当前样品制备、基于分析化学的技术和数据分析以及采用非靶向检测方法分析复杂食品基质的局限性和挑战。

Some of the contaminants in food were known,while some were unknown,so non-targeted work flows for chemical hazard analyses were highly desirable in food safety and integrity fields to ensure human health.Two different analytical strategies,non-targeted metabolomics and chemical database filtering,could be used to screen unknown contaminants in food matrices.In this paper,an overview was provided in the current sample preparation,analytical chemistry-based techniques and data analysis,as well as the limitations and challenges of non-targeted detection methods for analyzing complex food matrices.