女性冠状动脉微血管性心绞痛的诊断及治疗进展

Diagnosis and Treatment of Microvascular Angina in Female

微血管性心绞痛的病因目前不完全清楚,目前病因多认为与冠状动脉内皮功能障碍、冠状动脉微循环功能不全、炎症反应、胰岛素抵抗、雌激素水平不足、冠状动脉痉挛等微血管性心绞痛的发病密切相关。女性微血管性心绞痛发病率远远高于男性,女性发病多在绝经后,年龄区间多在50~55岁,故目前女性微血管性心绞痛的诊断及治疗得到了极大的重视,诊断及治疗方案也被单独提出研究,现对女性微血管性心绞痛的诊断方法及药物治疗进展进行阐述。

The etiology of the microvascular angina pectoris is not entirely clear. Previous studies indicate that the coronary endothelial dysfunction, endothelial activation and inflammation, insulin resistance, estrogen deficiency and coronary artery spasm are closely related to the onset of microvascular angina. However, the incidence of angina in female is much higher than in male. The microvascular angina in female mostly happens in menopause. Ages range between 50 to 55 years old, so nowadays the diagnosis and treatment of microvascular angina in women draw great attention, and diagnosis and treatment were also studied separately. This article reviews the current progress of diagnosis and drug treatment of microvascular angina pectoris in female.