单核细胞/高密度脂蛋白比值与心血管疾病的研究进展

Monocyte/High-density Lipoprotein Ratio and Cardiovascular Disease

心血管疾病是当前全球卫生系统的重要负担之一,具有高患病率、高致残率和高死亡率的特点。研究表明其高危因素包括糖尿病、高血压、吸烟、高胆固醇血症、肥胖和阳性家族史等,但这些有时并不足以对心血管疾病风险进行评估。近来研究提出单核细胞/高密度脂蛋白比值可作为新的潜在的炎症标志物。现就单核细胞/高密度脂蛋白比值与心血管疾病的相关性研究进展做一简要概述。

Cardiovascular disease is one of the important burdens of the current global health system, characterized by high prevalence, disability and mortality. Studies have shown that high-risk factors include diabetes, hypertension, smoking, hypercholesterolemia, obesity and positive family history, but these are sometimes not enough to assess cardiovascular risk. Recently, the monocyte/high-density lipoprotein ratio has been proposed as a new potential inflammatory marker. This article provides a brief overview of the research progress on the relationship between monocyte/high-density lipoprotein ratio and cardiovascular diseases.