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血凝酶+泮托拉唑治疗上消化道出血的临床价值分析

Clinical Value of Hemagglutinase Combined with Pantoprazole in the Treatment of Upper Gastrointestinal Hemorrhage
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摘要 目的:研究上消化道出血患者采用泮托拉唑联合血凝酶进行治疗的临床价值。方法:选择在我院接受治疗的56例上消化道出血患者,以随机分组的方式分成对照组(28例)和治疗组(28例)。对照组采用泮托拉唑进行治疗;治疗组采用泮托拉唑联合血凝酶进行治疗。比较两组上消化道出血症状消失时间和治疗总时间、药物治疗总有效率、用药导致的不良反应、用药前后应激指标和炎症因子水平。结果:治疗组患者上消化道出血症状消失时间和治疗总时间短于对照组;治疗组总有效率高于对照组;治疗组不良反应少于对照组;治疗组用药前后应激指标和炎症因子水平改善效果优于对照组。上述研究相关数据组间差异有统计学意义(P<0.05)。结论:上消化道出血患者采用泮托拉唑联合血凝酶进行治疗,能够大幅度控制炎症因子,改善应激指标,缩短治疗和恢复时间,减少由于用药原因导致的不良反应,使治疗效果得到显著性提升。 Objective:To study the clinical value of pam Tora zole combined with hemagglutinase in the treatment of upper gastrointestinal hemorrhage.Methods:56 patients with upper gastrointestinal bleeding were randomly divided into control group(n=28)and treatment group(n=28).The control group was treated with pamtorazole and the treatment group with pamtoraazole combined with hemagglutinase.The time of disappearance of symptoms of upper gastrointestinal hemorrhage,the total time of treatment,the total effective rate of drug treatment,the adverse reactions caused by drug use,the stress index and the level of inflammatory factors before and after treatment were compared between the two groups.Results:the symptoms of upper gastrointestinal hemorrhage in the treatment group The time of disappearance and the total time of treatment were shorter than that of the control group;the total effective rate of the treatment group was higher than that of the control group;the adverse reaction of the treatment group was less than that of the control group;the improvement effect of stress index and inflammatory factor level in the treatment group was better than that in the control group.There was a significant difference between the two groups(P<0.05).Conclusion:Pamtorazol combined with hemagglutinase can significantly control inflammatory factors,improve stress index,shorten treatment and recovery time,and reduce adverse reactions caused by drug use in patients with upper gastrointestinal hemorrhage.The therapeutic effect was significantly improved.
作者 徐卫喜 XU Wei-xi(Department of Gastroenterology,Wannian People's Hospital,Shangrao Jiangxi 335500,China)
出处 《药品评价》 CAS 2019年第14期24-26,共3页 Drug Evaluation
关键词 上消化道出血 泮托拉唑 血凝酶 应激指标 炎症因子 Upper Gastrointestinal Hemorrhage Pantoprazole Hemagglutinase Stress Index Inflammatory Factor
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